What is MicroLactin?
MicroLactin is essentially milk. It contains all the anti-inflammatory properties of milk, including enzymes, cytokines, EGF, antiproliferative agents, and antioxidants (Goldman et al. 1996). However, this milk is different than normal milk because it is taken from "hyper-immunized"Ãƒâ€šÃ‚Â cows (which are treated in New Zealand). These "hyper-immunized"Ãƒâ€šÃ‚Â cows have been injected with bacteria that trigger an immune response, leading to an increase in antibodies and anti-inflammatory agents. The "hyper-immune,"Ãƒâ€šÃ‚Â anti-inflammatory agents are then passed into the milk, which is then collected and passed through a series of processes to remove fat, casein, and macronutrients that have a weight of greater than 1,000 daltons [Beck, 1997]. A very concentrated form of whey with high concentrations of anti-inflammatory agents is what is left of the milk. MicroLactin is concentrated milk protein and is non-steroidal.
What does it do? MicroLactin and its concentrated milk protein claims to decrease blood pressure, reduce cholesterol, lessen inflammation, accelerate muscle recovery after exercise, and improve overall joint health. It also claims to improve range of motion and mobility, while reducing stiffness in joints.
How does it work?
Though the mechanism of its anti-inflammatory activities is not fully known, researchers have shown that neutrophil and lymphocytes are affected. The secondary, neutrophil-mediated phase of carrageenan-induced inflammatory response is suppressed and neutrohphil emigration is inhibited. One study done by Ormrod, et al, showed that there was an increase in the amount of neutrophil and a decrease in the number of lymphocytes in circulation. The high concentration of anti-inflammatory agents found in MicroLactin may also block the mitogenic response of lymphocytes, as well as block the response of lymphocyte to foreign histocompatibility antigens. There are a number of patents with MicroLactin, including one, the Prevention and Treatment of rheumatoid arthritis, and two, the Method of Treating Inflammation, both done by Dr. Beck and team.
One research project, called The Ohio Survey, was done by Beck and Stolle Immune Milk in Cincinnati, Ohio. During 1960 to 1996, they gave out hyper-immune milk powder to patients with osteoarthritis and between 1992 and 1996, they asked these same patients to record and rate their joint symptoms with a questionnaire. Overall, 83.7% of the people that took the milk concentrate reported an improvement in their joint pains. Another study was done by Zenk, et al, in 2002 which examined the Effects of Milk Protein Concentrate on the Symptoms of Osteoarthritis in Adults. This was a double-blind, placebo-controlled study that took 6 weeks. All participants in this study were physician-diagnosed with osteoarthritis. The participants were divided into three groups: group 1 was given 2g of milk protein concentrate, group 2 was given 500 mg of glucosamine sulfate, and group three was given a placebo. The WOMAC Osteoarthritis index score was used to assess their symptoms of osteoarthritis. The results showed that the average age was 59 yrs, and that there was a significant improvement in all 4 scores of the WOMAC index in the milk protein concentrate group, a significant improvement in one score of the glucosamine sulfate group, and no significant changes in any of the scores for the placebo group (Zenk, et al, 2002).
Dosage Recommendations and Safety.
It is recommended that 2 grams be taken twice daily for the first 7-10 days, and 1 gram daily in the days following, but the age level, health status, and tolerance to the supplement (i.e. lactose-intolerance) should also be of consideration. People who are allergic to cow's milk, for example, should not use MicroLactin. MicroLactin may also interfere with the activity of tetracycline-type antibiotics. MicroLactin does have a GRAS seal, which stands for Generally Regarded as Safe, and it is the highest level of safety review that a nutriceutical or dietary supplement can achieve (http://www.humaneticsingredients.com).
All the research on milk protein concentrate concluded that this product reduced joint pains, decreased inflammation, and increased mobility. Though the majority of these studies are sponsored by the same people that endorse it, all showed similar results in inflammation and joint pains. While the mechanisms are not fully known, the risks are basically the same as drinking a large amount of milk (i.e. little risk), while the benefits are considerable.
Carlon M. Colker MDa, Melissa Swain CES MS a*, Leila Lynch RD MSa and Daniel A. Gingerich DVM, MSb. Effects of a milk-based bioactive micronutrient beverage on pain symptoms and activity of adults with osteoarthritis: a double-blind, placebo-controlled clinical evaluation.
C. Woods DVM, MS and D. Gingerich, DVM, MS. Technical Brief: Pharmacology of Microlactin http://www.vpl.com/product_info/duralactin/Duralactin%20Pharmacology.pdf
Goldman AS, Goldblum RM, Hanson LA. Anti-Inflammatory Systems in Human Milk. PubMed. 1990; 262:69-76
Goldman A. S., Goldblum R. M., Schmalstieg F. C. Protective properties of human milk. Perinatal nutrition. Part III. Walker W. A. Watkins J. B. eds. Nutrition in Pediatrics. Basic Science and Clinical Applications 2nd ed. 1996:449-457 B. C. Decker Hamilton, ON, Canada.